Portsmouth and Southampton FC have a Vitality Women’s FA Cup 3rd Round clash three days before a league meeting at Fratton Park.
The first of back-to-back south coast derbies sees Pompey play the Saints at Westleigh Park, before the pair meet again on a bigger stage for the midweek FAWNL match.
Burnley have perhaps the most attractive fixture, with the mid-table National League Northern Premier side hosting current Championship leaders Liverpool.
Three regional league sides and one team from the seventh tier are still involved in the competition, with the chance of being paired with WSL opposition in Monday’s fourth round draw.
Clapton are the lowest ranked team left in the Cup, second and unbeaten in the Greater London Premier they visit a Plymouth Argyle side four tiers their senior, after winning their last two ties away from home on penalties.
Ashford Town (Middlesex) are also without defeat and top of the London & South East Premier, ahead of their big home clash with London City Lionesses, who sit second in the Championship with a three-level advantage over their hosts.
Stourbridge, one point off the West Midlands League leadership, have a big test in entertaining Sheffield United but have already accounted for Derby County.
Northampton Town have won all their games in the East Midlands Premier but now must travel to take on FAWNL Division 1 Midlands title-chasers Lincoln City.
Sunday 12 December
AFC Wimbledon v Ipswich Town (AFC Wimbledon, 2pm)
Ashford Town (Middx) v London City Lionesses (Ashford Town Middx FC, 2pm)
Bridgwater United v Crystal Palace (Bridgwater Utd FC, 2pm)
Brighouse Town v Sunderland (Brighouse Town AFC, 1pm)
Bristol City v Lewes (Robins High Performance Centre, 3pm)
Burnley v Liverpool (Lancashire FA County Ground, 1pm)
Chesham United v Billericay Town (Chesham Utd FC, 1pm)
Chorley v Newcastle United (Burscough FC, 2pm)
Gillingham v Charlton Athletic (Rochester United Sports Ground, 1pm)
Huddersfield Town v Loughborough Lightning (Shelley CFC, 1pm)
Leeds United v Durham (Tadcaster Albion FC, 1pm)
Lincoln City v Northampton Town (Lincoln Moorlands Railway FC, 2pm)
Liverpool Feds v Blackburn Rovers (Jericho Lane Sports Hub, 2pm)
Plymouth Argyle v Clapton (Saltash Utd FC, 1pm)
Portsmouth v Southampton FC (Havant & Waterlooville FC, 2pm)
Southampton Women’s FC v Exeter City (Alresford Town FC, 2pm)
Stoke City v Nottingham Forest (Norton Sports Club, 1pm)
Stourbridge v Sheffield United (Stourbridge FC, 1pm)
Watford v Coventry United (Kings Langley FC, 3pm)
West Bromwich Albion v Long Eaton United (Sutton Coldfield Town FC, 1pm)
Winning teams from 3rd Round ties receive £1,250, losing sides get £315.
The Fourth Round draw on Monday 13 December, will be broadcast live on TalkSPORT at 7pm.