The Genero Adran League’s top two are to clash in the Trophy quarter-finals while second-tier Cascade take on Swansea City.
Cardiff City are the current holders and Adran Premier leaders but have a testing away tie to second-placed The New Saints.
After eliminating top-flight Cardiff Met in the Round of 16 on Sunday, Cascade YC are rewarded with a home tie against the Swans.
Barry Town United will welcome Wrexham to Jenner Park and Briton Ferry Llansawel have home advantage over Aberystwyth Town.
Genero Adran Trophy Quarter-Finals
Barry Town United v Wrexham
Briton Ferry Llansawel v Aberystwyth Town
The New Saints v Cardiff City
Cascade v Swansea City
Ties to be played be on Sunday 8 December.
