The Genero Adran Premier kicks off the new campaign on 4 September, with defending champions Swansea City taking on runners-up Cardiff Met.
Cardiff City start at home to Pontypridd United, promoted Abergavenny host Aberystwyth Town.
Elsewhere on the opening weekend, The New Saints and Barry Town United meet at Park Hall.
Sunday 4 September
Abergavenny v Aberystwyth Town
Cardiff City FC v Pontypridd United
Swansea City v Cardiff Met
The New Saints v Barry Town United
Click here for the full Phase One list.