Portsmouth play Hashtag United whom they trail by six points in the FA Women’s National League Southern Premier Division but with two games in hand.
Pompey go into the game with the return of forward Daisy McLachlan, who re-joined the club this week from AFC Wimbledon after spells at London Bees and Oxford United.
Third-placed Rugby Borough are home to Cardiff City Ladies, Chatham Town take on fifth-placed Oxford United and Billericay Town entertain a winless London Bees.
FA Cup commitments mean just one match in the Northern Premier, where West Brom welcome Liverpool Feds whom they are four places – but only five points – behind.
Fifth plays first in Division 1 Midlands with Northampton Town up against Loughborough Lightning, second-placed Northampton Town v Loughborough Lightning second-placed Boldmere are at Leafield.
Third versus fourth in Division 1 North sees Middlesbrough meet Leeds United, while leaders Barnsley WFC host Durham Cestria and second-placed Hull City are home to Chester le Street.
Division 1 South East leaders AFC Wimbledon have home advantage over AFC Sudbury, second-in-the-table Norwich City go to Cambridge United.
Exeter City have ten straight wins in Division 1 South West ahead of facing Southampton Women, AFC Bournemouth also boast a perfect record before the match with Swindon Town.
Sunday 14 January (2pm)
NORTHERN PREMIER DIVISION
West Bromwich Albion v Liverpool Feds (Redditch Utd FC, 3pm)
SOUTHERN PREMIER DIVISION
Billericay Town v London Bees (Billericay Town FC)
Chatham Town v Oxford United (Chatham Town FC)
Portsmouth v Hashtag United (Havant & Waterlooville FC)
Rugby Borough v Cardiff City LFC (Rugby Borough FC)
DIVISION 1 MIDLANDS
Leafield Athletic v Boldmere St Michaels (Castle Vale Stadium)
Lincoln City v Leek Town (Moorlands Sports Ground)
Northampton Town v Loughborough Lightning (Fernie Fields Sports Ground)
Sheffield FC v Notts County (Sheffield FC)
Sporting Khalsa v Solihull Moors (Sporting Khalsa FC)
Sutton Coldfield Town v Peterborough United (Central Ground)
DIVISION 1 NORTH
Barnsley WFC v Durham Cestria (Sheffield Olympic Legacy Park)
Chorley v Norton & Stockton Ancients (Blainscough Park)
Doncaster Rovers Belles v Stockport County (Moorends Miners Welfare)
FC United of Manchester v York City (FC United)
Hull City v Chester le Street Town (Barton Town FC)
Middlesbrough v Leeds United (Stockton Town FC)
DIVISION 1 SOUTH EAST
AFC Wimbledon v AFC Sudbury (Carshalton Athletic FC)
Ashford Town v Actonians (Ashford Town [Middlesex] FC)
Cambridge City v Chesham United (Haverhill Rovers FC)
Cambridge United v Norwich City (St Neots Town FC)
Haywards Heath Town v Queens Park Rangers (Haywards Heath Town FC)
London Seaward v Worthing (Redbridge FC)
DIVISION 1 SOUTH WEST
AFC Bournemouth v Swindon Town (Ringwood Town FC)
Exeter City v Southampton Women (Exwick Sports Hub)
Portishead Town v Keynsham Town (Portishead Town FC)
Torquay United v Abingdon United (Devon County FA)