Cardiff City await the winners of the tie between Abertillery Belles and Penclawdd in the Bute Energy Welsh Cup 1st Round.
Either Abertillery of the South West Wales League of Penclawdd of the West Wales League will be up against the Cup winners of the last thre seasons.
North East Wales League outfit Llanystumdwy also have a massive test when welcoming Wrexham, likewise Talycopa who take on Swansea City.
There is one all-Adran Premier clash, as Cardiff Met entertain Barry Town United.
North
Felinheli v Llangefni
Rhyl v Aberystwyth Town
Llanystumdwy v Wrexham
Llandudno v Connah’s Quay Nomads
NFA v Airbus UK Broughton
Pwllheli v The New Saints
South
Cwmbran Celtic v Croesyceiliog or Cascade
Abertillery Belles or Penclawdd v Cardiff City
Wattsville or Penydarren v Llanelli Town
Cardiff Wanderers v Caldicot Town
Swansea University v Carmarthen Town
Llantwit Fardre or Cambrian United v Johnstown
Pontypridd United v Penybont
Talycopa v Swansea City
Cardiff Met v Barry Town United
Taffs Well v Briton Ferry Llansawel
All ties will be played on Sunday 20 October.