North London rivals, Arsenal and Tottenham Hotspur, both go in search of seventh successive wins as the Gunners face Birmingham City, while Spurs have a massive match at Manchester United.
Fixtures for Sunday 4th November
Arsenal v Birmingham City (Boreham Wood FC, 12.30) – live on BBC Red Button / BBC Sport
Liverpool v Manchester City (Tranmere Rovers FC, 2pm) – live on FA WSL Facebook
Reading v Bristol City (Wycombe Wanderers FC, 2pm)
West Ham United v Chelsea (Rush Green Stadium, 3pm)
Yeovil Town v Everton (Dorchester Town FC, 3pm
Durham v Lewes (Durham City FC, 12:00)
Manchester United v Tottenham Hotspur (Leigh Sports Village, 12:00) – live on MUTV
Charlton Athletic v London Bees (VCD Athletic, 2pm)
Sheffield United v Leicester City WFC (2pm)
Aston Villa v Millwall Lionesses (Boldmere St Michaels FC, 3pm)
Arsenal are top scorers with six straight wins under their belt as they prepare to host third-place Birmingham City, who might not be nearly as prolific in front of goal but have conceded as few as the Gunners.
Manchester City are the only other scorers of note in the top flight and they visit a Liverpool side who have won three and lost three.
West Ham are home in a big London derby will hope to take advantage of Chelsea’s lack of league goals, although the Blues will have gained confidence from a 6-0 Champions League victory in midweek.
Reading and Bristol City go into their meeting with almost identical records, with the mid-table Royals just a goal ahead of the Vixens.
Yeovil Town lost out in a basement battle with Brighton last week and they now face another such match with Everton their visitors.
Tottenham Hotspur have won all their Championship games to date but now face their stiffest task, away to unbeaten and second-placed Manchester United who will be backed by a big crowd.
Any slip up for the Reds could allow Charlton Athletic to overtake them, as they have home advatntage against London Bees who have lost five of their seven matches.
Lewes make the long trip to Durham, who have yet to suffer defeat with only two goals conceded in six outings.
Sheffield United v Leicester City
The bottom two go head-to-head as Aston Villa meet Millwall. Both are still without a win but whereas Villa gave Spurs something of a fright last time out, the Lionesses were thrashed in a local derby.
Sheffield United will make their Olympic Legacy Park debut when they take on Leicester City. The Blades were boosted by a 1-0 win at Crystal Palace last Sunday and have already played the Foxes in a pre-season draw.